AKT-IN-VIII - CAS# 612847-09-3 60211 Chemical Name: N-(1

Chemical Name: N-(1

a novel and simple chemically defined xeno-free culture system was developed that allows for long-term expansion of human pluripotent stem cells without FGF or TGF-beta pathway activation

InChiKey: UJLAWZDWDVHWOW-YPMHNXCESA-N

IC50 Value: 10±0

TDZD-8 decreased proliferation and induced apoptosis of GL261 glioblastoma cells in vitro

AKT-IN-VIII - CAS# 612847-09-3 60211 Chemical Name: N-(1AKT IN VIII, CAS No. 612847 09 3, also known as AKTi 1 2, is a potent, selective and ell permeable, allosteric inhibitor of Akt 1 and 2, which efficiently inhibits CaMKI activity and aryl hydrocarbon receptor pathway. AKT IN VIII suppresses hyperthermia induced Ndrg2 phosphorylation in gastric cancer cells. AKT IN VIII displays good selectivity against a panel of 70 other kinases with micromolar inhibition against some kinases, for example, calcium