Lovastatin Size:Solid 2 mg 31)32/h3-5

31)32/h3-5

2 µM concentration in cellular assays to investigate its effects on the PI3K/AKT signaling pathways

CAS Number: 2097381-85-4

Formula: C25H21F3N4O3S

InChi: InChI=1S/C19H28N4O3/c1-5-14-11-15(13(2)24)16(25)12-17(14)26-10-8-6-7-9-19(3

Lovastatin Size:Solid 2 mg 31)32/h3-5Lovastatin inhibits HMGCR, blocking the enzyme catalyzed transformation of 3 hydroxy 3 methylglutaryl CoA into mevalonate. Lovastatin is a statin natural product isolated from numerous sources including the Pleurotus ostreatus oyster mushroom, demonstrating hypocholesterolemic and antiproliferative properties. The biosynthesis of cholesterol requires mevalonate as a building block and elimination of mevalonate generation subsequently interrupts