c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 50ul Hepatocytes The N-terminus is poorly conserved

The N-terminus is poorly conserved and may impart additional roles in developmental regulation

SOX17 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate

is a 648 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain

which can be present in 3 to 11 copies

The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions

c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 50ul Hepatocytes The N-terminus is poorly conservedThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a