DNA-PKCS Polyclonal Antibody, 50ul[BT-AP02673] Measuring Instruments The subcellular localization and function

The subcellular localization and function of this protein are modulated by post-translational modifications

The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase

The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein

with symptoms including severe mononucleosis and malignant lymphoma

Due to a segmental duplication

DNA-PKCS Polyclonal Antibody, 50ul[BT-AP02673] Measuring Instruments The subcellular localization and functionPRKDC (protein kinase, DNA activated, catalytic polypeptide) encodes the catalytic subunit of the DNA dependent protein kinase (DNA PK). It functions with the Ku70 Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3 PI4 kinase family.