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MED15 Polyclonal Antibody, 100ul Filtration 3-galactosyltransferase (beta3GalT) gene family

SKU: 96337547157

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MED15 Polyclonal Antibody, 100ul Filtration 3-galactosyltransferase (beta3GalT) gene familyThe protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.

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Description

3-galactosyltransferase (beta3GalT) gene family

HNRNPUL2 (Heterogeneous Nuclear Ribonucleoprotein U-Like 2) is a Protein Coding gene

The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12

Only a few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding

Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size

MED15 Polyclonal Antibody, 100ul Filtration 3-galactosyltransferase (beta3GalT) gene familyThe protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.

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