TIF1 beta(Phospho-Ser824) Rabbit Polyclonal Antibody, 50ul Cytokines Mutations in MSX2 are associated

Mutations in MSX2 are associated with parietal foramina 1 and craniosynostosis type 2

The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1)

The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface

It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic

The encoded membrane-bound protein localizes to the cell surface

TIF1 beta(Phospho-Ser824) Rabbit Polyclonal Antibody, 50ul Cytokines Mutations in MSX2 are associatedThe protein encoded by this gene mediates transcriptional control by interaction with the Kruppel associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc binding domains a RING a B box type 1 and a B box type 2 and a coiled coil region.