GRK 7 Polyclonal Antibody, 100ul Mini dry bath While the interaction with CBL

While the interaction with CBL is apparently mediated via the hydrophobic region of this domain

It is required for the activation of the transcription factors NF-kappaB and AP-1

Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures

This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis

phospholipase C gamma 1 causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi

GRK 7 Polyclonal Antibody, 100ul Mini dry bath While the interaction with CBLGRK7 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. It is specifically expressed in the retina and G protein coupled receptor kinase 7 has been shown to phosphorylate cone opsins and initiate their deactivation.