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PROF1 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation TP53I3 is induced by the

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PROF1 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation TP53I3 is induced by theThis gene encodes a member of the profilin family of small actin binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.

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Description

TP53I3 is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death

Mutations in this gene are associated with the disorders multiple endocrine neoplasia

Upon phosphorylation| this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement

Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices

NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65| RELB| NFKB1/p105| NFKB1/p50| REL and NFKB2/p52

PROF1 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation TP53I3 is induced by theThis gene encodes a member of the profilin family of small actin binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.

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