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N33 Polyclonal Antibody, 100ul Vacuum Filter kidney and heart tissue

SKU: 85622727792

4.2
USD123.75 USD154.75

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N33 Polyclonal Antibody, 100ul Vacuum Filter kidney and heart tissueTUSC3 is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene.

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Description

kidney and heart tissue

and it encodes a protein which is 83% identical to the KDELR1 gene product

The activity of this protein is specific for phosphatidylinositol 4|5-bisphosphate and phosphatidylinositol 3|4|5-trisphosphate

Alternative splicing results in multiple transcript variants encoding distinct isoform

This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis

N33 Polyclonal Antibody, 100ul Vacuum Filter kidney and heart tissueTUSC3 is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene.

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