PLB Polyclonal Antibody, 20ul Immunoassays Mutations in this gene have

Mutations in this gene have been reported to be associated with nonsyndromic hearing loss

This protein binds to the cAMP-response element and regulates cell proliferation

TUBGCP4 encodes a component of the gamma-tubulin ring complex

Weissenbacher-Zweymuller syndrome

The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter

PLB Polyclonal Antibody, 20ul Immunoassays Mutations in this gene haveThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the