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NFκB-p65(Phospho Ser281) Polyclonal Antibody, 50ul Peptide Library Activity of this protein is

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NFκB-p65(Phospho Ser281) Polyclonal Antibody, 50ul Peptide Library Activity of this protein isNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL RELA or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene RELA. Four

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Description

Activity of this protein is key in the development of neural tissues| particularly the eye

Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia

Fibrinogen-like protein 1 is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins

Overexpression of this gene has been shown to induce apoptosis in cells

The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors

NFκB-p65(Phospho Ser281) Polyclonal Antibody, 50ul Peptide Library Activity of this protein isNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL RELA or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene RELA. Four

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