SIRT1 (GlcNAc D548) Rabbit Polyclonal Antibody, 50ul Multi-Layer Cell Culture System the ATPase activity is thought

the ATPase activity is thought to be stimulated by both RNA and DNA

The protein may play an important role in the epigenetic control of chromatin structure and gene expression

Mutations in ITPR1 cause spinocerebellar ataxia type 15

This enzyme acts on histones| and its activity is important for chromatin assembly and chromosome integrity

kidney or liver

SIRT1 (GlcNAc D548) Rabbit Polyclonal Antibody, 50ul Multi-Layer Cell Culture System the ATPase activity is thoughtThis gene encodes a member of the sirtuin family of proteins homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular