Rat Leukemia Inhibitory Factor Receptor, LIFR ELISA Kit, 96T Culture Media Clathrin (see MIM 118955)-mediated endocytosis

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids

and can induce apoptosis and weakly activate the NF-kappaB transcription factor

and is therefore a potential candidate gene for this disorder

Type I interferon binding activates the JAK-STAT signaling cascade

It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity

Rat Leukemia Inhibitory Factor Receptor, LIFR ELISA Kit, 96T Culture Media Clathrin (see MIM 118955)-mediated endocytosisSignal transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells (By similarity).