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Rb Polyclonal Antibody, 50ul[BT-AP07686] Vacuum Filter characterized by loss of body

SKU: 7112954348

4.5
USD162.00 USD186.00

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Rb Polyclonal Antibody, 50ul[BT-AP07686] Vacuum Filter characterized by loss of bodyThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

characterized by loss of body fat

Diseases associated with C1QTNF8 include brain cancer

This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I)

Minichromosome maintenance complex component 3 encoded by MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication

This gene is aberrantly methylated in pancreatic cancer

Rb Polyclonal Antibody, 50ul[BT-AP07686] Vacuum Filter characterized by loss of bodyThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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