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Conflicting map positions at 3p14 or 3p21 have been reported for this gene

an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid

and ADCAIII often referred to as the pure cerebellar syndrome (SCA5)

Mutations in this gene contribute to mitochondrial complex 1 deficiency

14-3-3-pan Rabbit Polyclonal Antibody, 20ul Peptide Synthesis Boost your lab's efficiency withThis gene encodes a protein belonging to the 14 3 3 family of proteins members of which mediate signal transduction by binding to phosphoserine containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants which encode the