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Collagen IV alpha2 (Cleaved-Ser1485) Rabbit Polyclonal Antibody, 100ul Lysosome Catalytic activity:A phosphatidylcholine + H(2)O

SKU: 63578259946

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Collagen IV alpha2 (Cleaved-Ser1485) Rabbit Polyclonal Antibody, 100ul Lysosome Catalytic activity:A phosphatidylcholine + H(2)OAlpha chains of type IV collagen have a non collagenous domain (NC1) at their C terminus frequent interruptions of the G X Y repeats in the long central triple helical domain (which may cause flexibility in the triple helix) and a short N terminal triple helical 7S domain. Type IV collagen is the major structural component of glomerular basement membranes (GBM) forming a 'chicken wire' meshwork together with laminins proteoglycans and entactin

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Description

Catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate

which may mediate insulin signals to the actin cytoskeleton

The main features of this syndrome involve retinal abnormalities

Two chains of the factor are held together by 1 or more disulfide bonds

May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development

Collagen IV alpha2 (Cleaved-Ser1485) Rabbit Polyclonal Antibody, 100ul Lysosome Catalytic activity:A phosphatidylcholine + H(2)OAlpha chains of type IV collagen have a non collagenous domain (NC1) at their C terminus frequent interruptions of the G X Y repeats in the long central triple helical domain (which may cause flexibility in the triple helix) and a short N terminal triple helical 7S domain. Type IV collagen is the major structural component of glomerular basement membranes (GBM) forming a 'chicken wire' meshwork together with laminins proteoglycans and entactin

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