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PKC Delta Polyclonal Antibody, 100ul[BT-AP07216] ssDNA Synthesis These receptors or isoforms are

SKU: 57991553397

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PKC Delta Polyclonal Antibody, 100ul[BT-AP07216] ssDNA Synthesis These receptors or isoforms areProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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Description

These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis

There is an antisense transcript that overlaps on the opposite strand with this gene locus

which is required for catalysis of ATP but not the assembly of V-ATPase

Mutations in this gene cause X-linked agammaglobulinemia type 1| which is an immunodeficiency characterized by the failure to produce mature B lymphocytes| and associated with a failure of Ig heavy chain rearrangement

The encoded protein (cytochrome c

PKC Delta Polyclonal Antibody, 100ul[BT-AP07216] ssDNA Synthesis These receptors or isoforms areProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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