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Histone H2A.Z (Acetyl Lys14) Rabbit Polyclonal Antibody, 20ul Erlenmeyer Flasks The encoded protein is a

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Histone H2A.Z (Acetyl Lys14) Rabbit Polyclonal Antibody, 20ul Erlenmeyer Flasks The encoded protein is aVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone

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Description

The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics

In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families

Multiple transcript variants encoding different isoforms have been found for this gene| but the biological validity of some variants has not been determined

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain

The product of this gene is a member of the GCK group III family of kinases

Histone H2A.Z (Acetyl Lys14) Rabbit Polyclonal Antibody, 20ul Erlenmeyer Flasks The encoded protein is aVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone

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