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Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Mutations in this gene have

SKU: 55174476201

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Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Mutations in this gene haveThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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Description

Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency

Two alternatively spliced transcript variants encoding the same protein have been reported

The protein functions to initiate or augment the early phase of T-cell activation

Additionally| this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer

probable scaffold protein that may be involved in mRNA transport

Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Mutations in this gene haveThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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