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PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper which activates other proenzymes including

SKU: 48852137066

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PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper which activates other proenzymes includingPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

which activates other proenzymes including chymotrypsinogen and procarboxypeptidases

some of which encode the same protein

The central domain of this glycoprotein contains tandem repeats

and lowest expression in pancreas

Transcription factor GATA-4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function

PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper which activates other proenzymes includingPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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