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Rock-2 Polyclonal Antibody, 20ul[BT-AP07970] Cell Screening and Imaging Mutations in this gene have

SKU: 4388897714

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SEK97.20 SEK147.20

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Rock-2 Polyclonal Antibody, 20ul[BT-AP07970] Cell Screening and Imaging Mutations in this gene haveRho associated protein kinase 2 encoded by ROCK2 is a serine threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.

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Description

Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures

The transcript for PIGY is bicistronic

This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation

Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS)

LYPLA1 encodes a member of the alpha/beta hydrolase superfamily

Rock-2 Polyclonal Antibody, 20ul[BT-AP07970] Cell Screening and Imaging Mutations in this gene haveRho associated protein kinase 2 encoded by ROCK2 is a serine threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.

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