Dok-2 Polyclonal Antibody, 50ul[BT-AP02698] Hybridoma Antibody Sequencing it is now thought to

it is now thought to be a non-opioid receptor

This gene contains at least 14 exons| and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons

Eight alternatively spliced transcript variants have been described

This protein mediates the signals of the bone morphogenetic proteins (BMPs)| which are involved in a range of biological activities including cell growth| apoptosis| morphogenesis| development and immune responses

subcellular location:Expressed diffusely throughout the nucleus

Dok-2 Polyclonal Antibody, 50ul[BT-AP02698] Hybridoma Antibody Sequencing it is now thought toThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.