SMAD1 Polyclonal Antibody, 50ul[BT-AP14287] Gene Editing The encoded protein is localized

The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1

possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53

short basic domain

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The CKLF like MARVEL transmembrane domain containing 5 may exhibit tumor suppressor activity

SMAD1 Polyclonal Antibody, 50ul[BT-AP14287] Gene Editing The encoded protein is localizedThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell