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Glucosidase IIBeta Polyclonal Antibody, 50ul Miscellaneous The pyruvate dehydrogenase (PDH) complex

SKU: 28184485342

4.4
USD185.00 USD226.00

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Glucosidase IIBeta Polyclonal Antibody, 50ul Miscellaneous The pyruvate dehydrogenase (PDH) complexPRKCSH encodes the beta subunit of glucosidase II, an N linked glycan processing enzyme in the endoplasmic reticulum. Glucosidase 2 subunit beta is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in PRKCSH have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.

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Description

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide

However| it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer| stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways| such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase

Binding generally results in the modulation of the activity of the binding partner

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands

Hard and wear-resistant PP

Glucosidase IIBeta Polyclonal Antibody, 50ul Miscellaneous The pyruvate dehydrogenase (PDH) complexPRKCSH encodes the beta subunit of glucosidase II, an N linked glycan processing enzyme in the endoplasmic reticulum. Glucosidase 2 subunit beta is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in PRKCSH have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.

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