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Rad17 Polyclonal Antibody, 20ul[BT-AP07600] Micro Centrifuge Tubes CLCC1 is expressed as four

SKU: 26121645346

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Rad17 Polyclonal Antibody, 20ul[BT-AP07600] Micro Centrifuge Tubes CLCC1 is expressed as fourThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint

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Description

CLCC1 is expressed as four isoforms due to alternative splicing events

thought to be involved in the stimulation of cell proliferation

The protein encoded by RAD23A plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome

RAD52 product was shown to bind single-stranded DNA ends

The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment

Rad17 Polyclonal Antibody, 20ul[BT-AP07600] Micro Centrifuge Tubes CLCC1 is expressed as fourThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint

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