PLB Polyclonal Antibody, 100ul Immunology Expression of this gene is

Expression of this gene is almost exclusively in the brain

The ROS generated by family members have been implicated in numerous biological functions including host defense

It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region

Pseudogenes of this gene have been defined on chromosomes 14 and 17

member 2 (NR1A2)

PLB Polyclonal Antibody, 100ul Immunology Expression of this gene isThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the