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Phospho-5-LO (S523) Polyclonal Antibody, 50ul Digital Burette the encoded protein was initially

SKU: 22294472235

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Phospho-5-LO (S523) Polyclonal Antibody, 50ul Digital Burette the encoded protein was initiallyALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes

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Description

the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation

It is initially synthesized as a polyprotein precursor

Members of this family recognize the GATA motif which is present in the promoters of many genes

Designed to support the growth of CHO cells

Mutations at GCLC have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction

Phospho-5-LO (S523) Polyclonal Antibody, 50ul Digital Burette the encoded protein was initiallyALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes

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