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Syk(Phospho Tyr525) Polyclonal Antibody, 100ul Gloves Thr-816 (activation loop of the

SKU: 20173985284

4.4
PLN141.00 PLN175.00

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Syk(Phospho Tyr525) Polyclonal Antibody, 100ul Gloves Thr-816 (activation loop of theThis gene encodes a member of the family of non receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas.

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Description

Thr-816 (activation loop of the kinase domain) and Thr-958 (turn motif)

Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes

Expression of this gene is also associated with several types of cancer

The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling

which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al

Syk(Phospho Tyr525) Polyclonal Antibody, 100ul Gloves Thr-816 (activation loop of theThis gene encodes a member of the family of non receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas.

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