IKK alpha/beta(Phospho Ser176/177) Polyclonal Antibody, 100ul Endonucleases & Exonucleases This gene may show increased

This gene may show increased expression in the adrenal gland and lymphatic tissues

Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation

Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats| leucine-rich repeats| or the presence or absence of other protein-protein interacting domains

and pharmacologic properties

Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1)

IKK alpha/beta(Phospho Ser176/177) Polyclonal Antibody, 100ul Endonucleases & Exonucleases This gene may show increasedThis gene encodes a member of the serine threonine protein kinase family. The encoded protein a component of a cytokine activated protein complex that is an inhibitor of the essential transcription factor NF kappa B complex phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway thereby activating the transcription factor.